Semaglutide is a synthetic version of the hormone GLP-1, which is naturally produced by the body to regulate insulin secretion, glucose levels, and appetite. By activating the GLP-1 receptor, semaglutide can help control blood sugar levels and reduce hunger cravings, leading to a decreased caloric intake and promoting weight loss.
In clinical trials, semaglutide injections have demonstrated impressive weight loss results. The STEP trials (Semaglutide Treatment Effect in People with Obesity) evaluated the efficacy and safety of semaglutide in patients with obesity and overweight individuals with comorbidities such as type 2 diabetes. The trials showed that patients who received semaglutide injections lost significantly more weight than those who received a placebo, with an average weight loss of 15-20% over 68 weeks.
In addition to its weight loss benefits, semaglutide has also been shown to improve overall health by reducing cardiovascular risk factors such as blood pressure and cholesterol levels.